About the Holtzman Lab

My lab is interested in understanding the pathogenesis of Alzheimer’s disease and other neurodegenerative disorders. Abundant evidence suggests a central role for the amyloid-β (Aβ) peptide in Alzheimer’s disease (AD) pathogenesis. Changes in Aβ conformation from forms with predominantly random coil/alpha helix to both soluble and insoluble forms with high beta-sheet content appears to be a key event in AD. We are interested in developing a better understanding of Aβ metabolism in the CNS.
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About Dr. Holtzman

Dr. Holtzman is the Andrew B. and Gretchen P. Jones Professor and Chairman of Neurology, Professor of Developmental Biology, Associate Director of the Alzheimer’s Disease Research Center, and scientific director of the Hope Center for Neurological Disorders.
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Our Lab members

Learn about Holtzman lab members.
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Holtzman Lab Photos

Check out what the Holtzman Lab has been up to.
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