About the Fagan Lab

For the past ten years Anne has been investigating the mechanism(s) by which the E4 isoform of apolipoprotein E (apoE) is a risk factor for AD. Her multidisciplinary approach, utilizing biochemical and cell biological experiments coupled with analysis of in vivo transgenic mouse models of AD, has been instrumental in defining an important role for apoE in the metabolism of amyloid-b (Abeta), the protein that accumulates and forms plaques in the AD brain.
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About Dr. Fagan

Anne Fagan is a Research Associate Professor of Neurology

In 1995, Anne was recruited by Dr. David Holtzman, a long-time colleague, to gain training in Alzheimer’s Disease (AD) and help establish his lab at Washington University School of Medicine, and subsequently received her faculty appointment in the Department of Neurology in 1997.
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Our Lab Members

Learn about Fagan lab members
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Contact the Fagan-Niven Lab
E-mail: fagana@neuro.wustl.edu
Phone: (314) 362-3453 – office
(314) 747-0286 – lab

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