Current Lab Members

Lab Members

Melissa Sullivan
sullivanm@neuro.wustl.edu

Melissa has been with Washington University for over 11 years and joined the Bateman lab in 2015. Melissa manages and coordinates the Bateman Lab studies. She collaborates with many different departments such as CARS unit, Dietary, Anesthesia, ADRC, and Imaging to complete studies successfully. Melissa prides herself on the relationships that are built with participants and ensures that they are given the utmost respect when contributing to Bateman research.
Wendy Sigurdson, BScN, MHSc, RN
sigurdsonw@neuro.wustl.edu

Wendy is a Clinical Research Nurse in Neurology and has been with Dr. Bateman since April of 2007. Prior work experience includes Research for the Department of Neurosurgery. She received her BScN at McMaster University in Canada and her MHSc here at Washington University. Her focus is DIAN and DIAN-TU, but also assists with the ongoing A-beta and Tau studies. She enjoys working with Dr. Bateman and the team because of the amazing, cutting edge research.
Tamara Donahue, BSN, MS, RN
donahuet@neuro.wustl.edu

Tamera is a Clinical Research Nurse Coordinator in Neurology. Current studies include DIAN, DIAN-TU, and A-beta/ tau studies in Dr. Bateman’s lab. She completed her Diploma Nurses training at The Jewish Hospital School of Nursing, her Bachelor of Science degree in nursing at University of MO, St. Louis and a master’s degree in Clinical Research Management at Washington University. Her career has spanned various areas of clinical and research nursing including Cardiology, Imaging, Cardiothoracic Surgery and Neurology.
Norelle C. Wildburger, Ph.D.
n.wildburger@wustl.edu

Norelle is a postdoctoral fellow in the Bateman Lab. She is leading a clinical study in a hospice population where participants are isotopically labeled prior to passing. The goal is to quantify neuronal metabolism, it’s correlation with tau tangles, and the half-life of amyloid plaques using SILK-SIMS imaging. In addition to this, she characterizes and quantifies pathologically relevant proteins in their intact state (i.e., Top-down) to characterize the full spectrum of proteoforms (all protein products of a single gene) in brain and cerebral spinal fluid.

 

Clinical Study in a Hospice Population Video

Nicolas Barthélemy, Ph.D.
barthelemyn@neuro.wustl.edu

Dr. Barthélemy obtained his Ph.D. degree in Analytical Chemistry from the University of Strasbourg. He specializes in protein characterization and quantitation by mass spectrometry. He joined Dr. Bateman’s laboratory as Postdoctoral Associate in 2015 and is pursuing his research on tau protein implication in Alzheimer Disease and others tauopathies.
Chihiro Sato, Ph.D.,
satoc@neuro.wustl.edu

Dr. Sato is a Research Instructor in the Department of Neurology. She is currently researching the kinetics of tau in the human central nervous system in vivo and in vitro. She is also interested in studying tau profile in Alzheimer’s disease and various tauopathies hoping to improve early diagnostics. 
Kwasi G. Mawuenyega, Ph.D.
mawuenyegak@neuro.wustl.edu

Kwasi joined the Bateman team in 2006. He is a biochemist and bioanalytical chemist specializing in the characterization and quantification of proteins by mass spectrometry. He oversees all proteomics method development in the lab. Specifically, he is responsible for conducting mass spectrometry analyses, overseeing the maintenance of the machines and identifying new mass spectrometry technologies to incorporate into the lab. Project areas include the development of methods for simultaneous measurement of Aß isoforms in human CSF and plasma to enable SILK and pharmacodynamics studies in Alzheimer’s disease. He also collaborates with Dr. Tim Miller to study the kinetics and pharmacodynamics of SOD1 protein in ALS in humans and rat models.As the lab safety manager, Kwasi is also responsible for lab safety compliance with the general principles of working with laboratory chemicals and biological materials.
Brendan Lucey, MD
LuceyB@neuro.wustl.edu

Dr. Lucey is an Assistant Professor in the Department of Neurology, sleep medicine division. He is a KL2 scholar pursuing a Master of Science degree in Clinical Investigation. Dr. Lucey’s research investigates how changes in sleep-wake activity alter amyloid-beta concentrations and kinetics.
James Bollinger, Ph.D.
bollingerj@neuro.wustl.edu

Dr. Bollinger’s studies have focused on the development and application of novel analytical techniques for the profiling of enzymes of clinical relevance. Specifically, he has utilized the triple-quadrupole ESI-MS/MS analytical platform to design reagents and assays that enable the sensitive and specific analysis of individual proteins as well as metabolite profiles derived from their enzymatic activity. In collaboration with multiple other labs, he has applied these assays to characterize relative abundance and kinetic profiles of several proteins with the greater intent of investigating in vivo roles in cellular homeostasis and disease progression. Current efforts in the Bateman lab are focused on IP-LC/MS method development for the assessment of alpha synuclein protein turnover kinetics in human cerebrospinal fluid.

Undergraduate Students

Taylor Avei
Taylor Avei is a third year undergraduate at Brigham Young University majoring in Biology. He is a participant in BioMed Rap program at Washington University in St. Louis. His interests in genetics and clinical research are what brought him to the Bateman lab for the summer of 2018. He is helping with the amyloid beta in human plasma project to study how different isoforms of amyloid beta can contribute to Alzheimerʻs Disease. Outside of the lab, Taylor loves playing and watching sports. Also he enjoys listening to music and watching movies.
Paige Lawler
Paige Lawler is a third year undergraduate student at Washington University in St. Louis majoring in Neuroscience and minoring in Spanish. Driven by an interest in the cause and development of neurodegenerative diseases, she joined the Bateman lab in the summer of 2018. She is assisting on the ApoE project to study and characterize the forms of ApoE that exist in the human CNS, with the goal of correlating these findings to AD pathology. Outside of the lab, Paige is a member of the Washington U. Cross Country and Track and Field team and enjoys traveling and hiking.
Kevin Li
Kevin Li is a fourth year undergraduate at Washington University in St. Louis, studying biomedical engineering and computer science. His interest in problem solving and applying computational methods to clinical research led him to join the Bateman Lab in the summer of 2018. He is currently studying amyloid-beta kinetics and its implications in Alzheimer's diagnoses for patient care. Kevin hopes to pursue higher level education in computer science after graduation. Outside of lab, Kevin enjoys playing tennis, watching hockey, and hanging out with friends.
Nipun Mallipeddi
Nipun Mallipeddi is a first year undergraduate at Washington University in St. Louis. Interests in clinical research and neuroscience led him to join the Bateman lab in the summer of 2017. He is helping with the Tau project to study how Tau kinetics change in the CSF of AD and Tauopathy patients. After college, he hopes to pursue an MD. Outside of the lab, Nipun enjoys learning about animals, reading, and coding.