Predictive Biomarkers of Conversion to Tourette Syndrome in Children with New-Onset Tics
TITLE OF THE STUDY:
Predictive Biomarkers of Conversion to Tourette Syndrome in Children with New-Onset Tics.
PURPOSE OF THE STUDY:
This study looks at children between the ages of 5 and 17 who are experiencing a recent onset of tics. Tics are repetitive, involuntary sounds or movements like eye blinking, sniffing, abdominal tensing or making small noises. The purpose of this research is to compare those children who go on to develop Tourette Syndrome (TS) with children whose tics have resolved.
WHO IS NEEDED?
- Volunteers must be 5-17 years old
- Volunteers must have a parent or guardian that is also willing to participate
- Volunteers must have tics that started within the last 3 months
WHAT IS INVOLVED IF I PARTICIPATE?
- Duration: There will be 4 study visits over about 12 months.
- Tests/procedures: Questionnaires, assessments, interviews, saliva sample for genetic testing, and MRI scan
- Risks: Risks will be discussed with volunteers as part of the informed consent process.
- Benefits: This study may help children with tics in the future.
- Compensation: Compensation is provided for time and effort.
WHO IS THE PRINCIPAL INVESTIGATOR (PI)?
Dr. Kevin Black
WHERE WILL THE STUDY TAKE PLACE?
Washington University School of Medicine