Completed Grant Funding

U10 NS44455 Racette (PI) 12/01/2007 – 04/30/2015

Parkinson Disease Neuroprotective Trial: Clinical Center

The goal of this project was to participate in an NIH-sponsored multicenter trial of a drug to slow the progression of PD.


P42 ES04696 (PI-Checkoway) 04/01/2009 – 03/31/2015 (NCE)

Effects-Related Biomarkers of Neurotoxic Exposures

This was a Program Project-type grant consisting of 9 research projects and 3 cores, all focused on developing biomarker approaches to assessing human and ecological health effects at hazardous waste sites. Project #5 (project director) pertains to risks for parkinsonism related to environmental toxicants and genetic markers of susceptibility.


R01ES017809-01A1 (PI-Seixas) 09/15/2010 – 04/30/2013

Characterization of manganese exposure biomarkers among welder apprentices

The purpose of this grant was to investigate blood and imaging biomarkers of manganese in previously unexposed welding apprentices.


University of Washington Alcohol and Drug Abuse Institute (PI-Searles Nielsen) 07/16/2014 – 11/15/2014

Innate DNA Demethylation Capacity as a Contributor to Smoking Initiation

The overall objective of the proposed research is to test the hypothesis that expression of selected genes that affect the capacity to demethylate DNA affects tobacco smoking initiation.


R01ES013743 (PI-Racette) 02/03/2007 – 11/30/2012 (NCS)

Epidemiology of Parkinsonism in Welders

The purpose of this study was to perform a case-control study of parkinsonism in career welders and same-sex sibling controls and to perform a cohort study to investigate the dose-responsiveness of parkinsonism in welders.


BJHF/ICTS (PI-Racette) 06/01/2009 – 05/20/2011

Neuropathology of Chronic Manganese Exposure

The purpose of this grant was to determine if South African manganese miners with chronic manganese exposure demonstrate a greater frequency of neuropathologic changes typical of PD than a reference cohort of gold miners.


R21ES017504 (PI-Racette) 09/01/2009 – 09/30/2011

Neuropathology of Chronic Manganese Exposure

The purpose of this grant was to determine if South African manganese miners with chronic manganese exposure demonstrate a greater frequency of neuropathologic changes typical of PD than a reference cohort of gold miners.


3R01ES013743-04S1 (PI-Racette) 06/01/2010 – 08/31/2010

Administrative Supplement to Support College Undergraduate Research

The purpose of this grant was to investigate the impact of parkinsonism on worker productivity and injuries in shipyard welders.


Michael J. Fox Foundation (PI-Racette) 05/01/2006 – 12/31/2010

Workplace Exposures and Biomarkers of Parkinsonism in Welders

The purpose of this study is to investigate the relationship between lifetime welding exposure and clinical and biomarkers of parkinsonism in a cohort of shipyard workers.


3R01ES013743-02S1 (PI-Racette) 06/01/2008 – 08/30/2008

Administrative Supplement to Support College Undergraduate Research

The purpose of this grant is to determine if parkinsonian signs in welders are associated with reductions in PD specific quality of life measures, worker absenteeism, or reductions in job grade.