Washington University in St. Louis Med School

ANNOUNCEMENT: We are thrilled to announce that Andrew Sauerbeck's SEQUIN report on synapse loss in AD and TBI is now in-press at Neuron!

About the Kummer Lab

Research in the Kummer lab and in our collaborative group is focused on the mechanisms of cellular damage in traumatic brain injury (TBI) and in Alzheimer’s disease, with a particular focus on synaptic and other forms of gray matter injury. TBI is a major cause of morbidity and mortality in the United States and worldwide, and a major risk factor for the development of Alzheimer’s disease. We use a suite of nano through mesoscale imaging tools including advanced microscopic and MRI-based measurements to characterize novel forms of injury in these conditions and explore their connections. We are particularly interested in developing translational methods to connect pre-clinical experiments with patients in the hospital—where the lab PI is a clinical neurointensivist specializing in TBI and other forms of acute brain injury—leveraging the advanced imaging facilities within and just outside the ICU (including an in-ICP PET scanner, 3 dedicated research MRI scanners, and a PET-MRI).