Rachel Darken, MD, PhD

Assistant Professor of Neurology

Phone314-362-4342

Emaildarkenr@neuro.wustl.edu

Board Certifications

  • Sleep Medicine
  • Neurology

Recognition

  • Glasgow-Rubin Memorial Achievement Citation (top 10% of the medical school class), 2004
  • Papanicolaou Medical Scientist Fellowship, 2003-2004
  • Vincent duVigneaud Award of Excellence, 2002
  • 4th Year Speaker award Molecular Cell Biology graduate program , 2002

Publications

  • Darken RS, Bogitch R, Leonard J, Perry A, McKinstry RC, Gutmann DH, Rubin JB. Brainstem glioma presenting as pruritus in children with neurofibromatosis-1. J Pediatr Hematol Oncol. 2009 Dec;31(12):972-6.
  • Bruna A, Darken RS, Rojo F, Ocaña A, Peñuelas S, Arias A, Paris R, Tortosa A, Mora J, Baselga J, Seoane J. High TGFbeta-Smad activity confers poor prognosis in glioma patients and promotes cell proliferation depending on the methylation of the PDGF-B gene. Cancer Cell. 2007 Feb;11(2):147-60.
  • Jenny A, Darken RS, Wilson PA, Mlodzik M. Prickle and Strabismus form a functional complex to generate a correct axis during planar cell polarity signaling. EMBO J. 2003 Sep 1;22(17):4409-20.
  • Yang J, Tan C, Darken RS, Wilson PA, Klein PS. Beta-catenin/Tcf-regulated transcription prior to the midblastula transition. Development. 2002 Dec;129(24):5743-52.
  • Darken RS, Scola AM, Rakeman AS, Das G, Mlodzik M, Wilson PA. The planar polarity gene strabismus regulates convergent extension movements in Xenopus. EMBO J. 2002 Mar 1;21(5):976-85.
  • Darken RS, Wilson PA. Axis induction by wnt signaling: Target promoter responsiveness regulates competence. Dev Biol. 2001 Jun 1;234(1):42-54.
  • Darken RS, Martin KL, Fisher MC. Metabolism during delayed hatching in terrestrial eggs of a marine fish, the grunion Leuresthes tenuis. Physiol Zool. 1998 Jul-Aug;71(4):400-6.