Meghan C. Campbell, PhD

Assistant Research Professor of Neurology

Phone314-362-8222

Emailmeghanc@wustl.edu

Research Interests

In general, Dr. Campbell’s research falls within the category of Cognitive and Clinical Neuropsychology, with emphasis on the cognitive and behavioral features associated with movement disorders, particularly Parkinson disease. Using a multidisciplinary approach that incorporates behavioral and neuroimaging techniques and principles from clinical science, cognitive psychology, and cognitive neuroscience, Dr. Campbell’s research extends beyond the characterization of cognitive functioning in movement disorders in an effort to elucidate the mechanisms and underlying psychological and neurobiological processes. More specifically, Dr. Campbell is interested in developing a better understanding of how neuropsychological functions relate to the neuropathology, treatment, and comorbid psychiatric conditions of movement disorders. This research has important implications for the understanding and treatment of movement disorders, as well as the more general advancement of knowledge regarding the functions of the basal ganglia and frontal-striatal circuitry.

Recognition

2008                       American Neuropsychiatric Association (ANPA) Young Investigator Award

2008                       Brain & Behavior Research Foundation (NARSAD) Young Investigator Award

Education

  • B.S., summa com laude, Psychology: University of Illinois, Urbana/Champaign, Illinois (1999)
  • Ph.D., Clinical Psychology: Indiana University, Bloomington, Indiana (2004)
  • Clinical Neuropsychology Internship, Southwest Consortium Psychology Internship: New Mexico VA Medical Center, Albuquerque, New Mexico (2004-2005)
  • Postdoctoral Research Scholar, Movement Disorders and Neuroimaging: Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri (2005-2008)

Publications

Campbell, M.C., Koller, J.M., Buddhala, C., Kotzbauer, P.T., Snyder, A.Z., and Perlmutter, J.S. (2015).  Cerebrospinal fluid proteins and resting-state functional connectivity in Parkinson disease.  Neurology, 84(24): 2413-21.

Buddhala, C, Loftin SK, Kuley BM, Cairns NJ, Campbell M.C., Perlmutter JS, and Kotzbauer PT. (2015). Dopaminergic, serotonergic, and noradrenergic deficits in Parkinson disease. Annals of Clinical and Translational Neurology, 2(10): 949-959.

Lucero, C., Campbell, M.C., Flores, H., Maiti, B., Perlmutter, J.S., and Foster, E.R. (2015).  Cognitive reserve and beta-amyloid pathology in Parkinson disease.  Parkinsonism and Related Disorders, 21(8): 899-904.

Eisenstein, S.A., Koller, J., Black, K., Campbell M.C., Lugar, H., Ushe, M., et al., (2014).  Functional anatomy of subthalamic nucleus stimulation in Parkinson disease.  Annals of Neurology, 76(2), 279-295.

Eisenstein, S.A., Dewispelaere, W.B., Campbell, M.C., Lugar, H., Perlmutter, J.S., Black, K.J., and Hershey, T. (2014).  Acute changes in mood induced by subthalamic deep brain stimulation in Parkinson disease are modulated by psychiatric diagnosis.  Brain Stimulation, 7(5), 701-708.

Campbell, M.C., Markham, J., Flores, H., Hartlein, J., Goate, A., Cairns, N., and Perlmutter, J.S. (2013).  Principal component analysis of PiB distribution in Parkinson and Alzheimer diseases.  Neurology, 81, 520-527.

Hill, K.K., Campbell, M.C., McNeely, M.E., Karimi, M., Ushe, M., Tabbal, S.D., Hershey, T., Flores, H.P., Hartlein, J.M., Lugar, H.M., Revilla, F.J., Videen, T.O., Earhart, G.M., and Perlmutter, J.S. (2013).  Cerebral blood flow responses to dorsal and ventral STN DBS correlate with gait and balance responses in Parkinson disease. Experimental Neurology, 241, 105-12.

Campbell, M.C., Black, K.J., Weaver, P.M., Lugar, H.M., Videen, T.O., Tabbal, S.D., Karimi, M., Perlmutter, J.S., and Hershey, T. (2012). Mood response to deep brain stimulation of the subthalamic nucleus in Parkinson’s disease. Journal of Neuropsychiatry and Clinical Neuroscience, 24, 28-36.

Brown, C.A., Campbell, M.C., Karimi, M.K., Tabbal, S.D., Loftin, S.K., Tian, L., Moerlein, S.M., Perlmutter, J.S. (2012).  Dopamine pathway loss in accumbens and ventral tegmental area predicts apathetic behavior in MPTP-lesioned monkeys.  Experimental Neurology, 236(1), 190-7.

Kotzbauer, P.T., Cairns, N.J., Campbell, M.C., Willis, A.W., Racette, B., Tabbal, S.D., and Perlmutter, J.S. (2012). Pathological accumulation of α-synuclein and Aβ in Parkinson’s disease with dementia.  Archives of Neurology, 69(10), 1326-31.