Alexandre R Carter, MD, PhD

Assistant Professor of Neurology

Phone314-454-7756

Fax314-454-7759

Emailcartera@neuro.wustl.edu

Related Links

Recognition

  • KO8 – NINDS. Resting state functional connectivity and interhemispheric interaction in health and neurologic disease, 2009
  • Amos Medical Faculty Development Program Award, Robert Wood Johnson Foundation. Interhemispheric Interactions in Brain Motor Networks, 2009
  • T32 Institutional Training Grant, Washington University in Saint Louis School of Medicine, Department of Neurology, 2007-2008
  • Barnes Jewish Hospital Foundation Center for Diversity and Cultural Competence Award, 2006
  • Invited speaker at NGF2000 Conference on nerve growth factor and related molecules (Montreal, Canada), 2000
  • National Medical Fellowship, Inc, Award for Science Journalism, 2000-2001

Publications

  • Urbin MA, Hong X, Lang CE, Carter AR. Resting-State Functional Connectivity and Its Association With Multiple Domains of Upper-Extremity Function in Chronic Stroke. Neurorehabil Neural Repair. 2014 Feb 18. [Epub ahead of print]
  • Carter AR, Shulman GL, Corbetta M. Why use a connectivity-based approach to study stroke and recovery of function? Neuroimage. 2012 Oct 1;62(4):2271-80.
  • Carter AR, Patel KR, Astafiev SV, Snyder AZ, Rengachary J, Strube MJ, Pope A, Shimony JS, Lang CE, Shulman GL, Corbetta M. Upstream dysfunction of somatomotor functional connectivity after corticospinal damage in stroke. Neurorehabil Neural Repair. 2012 Jan;26(1):7-19.
  • Crowner BE, Torres-Russotto D, Carter AR, Racette BA. Systemic weakness after therapeutic injections of botulinum toxin a: a case series and review of the literature. Clin Neuropharmacol. 2010 Sep-Oct;33(5):243-7.
  • Carter AR, Connor LT, Dromerick AW. Rehabilitation after stroke: current state of the science. Curr Neurol Neurosci Rep. 2010 May;10(3):158-66.
  • Carter AR, Astafiev SV, Lang CE, Connor LT, Rengachary J, Strube MJ, Pope DL, Shulman GL, Corbetta M. Resting interhemispheric functional magnetic resonance imaging connectivity predicts performance after stroke. Ann Neurol. 2010 Mar;67(3):365-75.
  • Carter AR, Shulman GL and Corbetta M. Chapter: Brain Mapping of Attention and Neglect after Stroke. Brain Repair After Stroke (upcoming), Cramer S. and Nudo R. editors.
  • Carter AR, Berry E, Schwartz PM, Segal RA. Regional expression of p75NTR contributes to neurotrophin regulation of cerebellar patterning. Mol Cell Neurosci. 2003 Jan;22(1):1-13.
  • Carter AR, Chen C, Schwartz PM, Segal RA. Brain-derived neurotrophic factor modulates cerebellar plasticity and synaptic ultrastructure. J Neurosci. 2002 Feb 15;22(4):1316-27.
  • Borghesani PR, Peyrin JM, Klein R, Rubin J, Carter AR, Schwartz PM, Luster A, Corfas G, Segal RA. BDNF stimulates migration of cerebellar granule cells. Development. 2002 Mar;129(6):1435-42.
  • Dubinsky B, Vaidya AH, Rosenthal DI, Hochman C, Crooke JJ, DeLuca S, DeVine A, Cheo-Isaacs CT, Carter AR, Jordan AD, Reitz AB, Shank RP. 5-ethoxymethyl-7-fluoro-3-oxo-1,2,3,5-tetrahydrobenzo[4,5]imidazo[1,2a]pyridine-4-N-(2-fluorophenyl)carboxamide (RWJ-51204), a new nonbenzodiazepine anxiolytic. J Pharmacol Exp Ther. 2002 Nov;303(2):777-90.
  • Carter AR, Segal RA. Rett syndrome model suggests MECP2 gives neurons the quiet they need to think. Nat Neurosci. 2001 Apr;4(4):342-3.
  • Herman AE, Galaburda AM, Fitch RH, Carter AR, Rosen GD. Cerebral microgyria, thalamic cell size and auditory temporal processing in male and female rats. Cereb Cortex. 1997 Jul-Aug;7(5):453-64.

Dr. Carter is an Assistant Professor in the Division of Stroke and Traumatic Brain Injury in the Department of Neurology and sees patients at the Comprehensive Outpatient Stroke Clinic in the Center for Advanced Medicine and at The Rehabilitation Institute of Saint Louis. Stroke is the leading cause of long-term disability in the United-States and the third leading cause of death at a cost of over $70 billion a year. For a long time it has been thought that nothing could be done to enhance a stroke patient’s recovery. This nihilistic view was fed by many long held beliefs about the brain that are oversimplifications, and by a lack of tools to measure and modulate brain activity. We now know that the brain is organized as a set of interconnected, distributed networks, that it is capable of self-repair and of adaptive plasticity when repair is not possible. Dr. Carter’s work is centered on understanding the mechanisms of brain plasticity at the network level to help promote better recovery after stroke. Different techniques that are being used to understand distributed brain networks include resting state functional connectivity MRI, non-invasive brain stimulation, as well as more traditional activity-based therapies. This work will also help clinicians better determine which patients are more likely to benefit from which therapies, and promote more of an evidence-based approach to neurorehabilitation. Dr. Carter is also active in promoting stroke awareness and the message of primary and secondary stroke prevention through his involvement in The Rehabilitation Institute’s Patient and Family Stroke Education Series and in the wider Saint Louis community.