Resident Research

While research is certainly not a required element of pediatric neurology residency training (several of our graduates elect to enter private practice), there are extensive research opportunities both within the division and throughout the medical school and university for those who desire. Our faculty members are engaged in many different areas of research from imaging to clinical trials to traditional bench research to educational studies.

Washington University prides itself on interdisciplinary collaborations. We have strong research relationships with areas such as radiology, psychology, hematology/oncology, molecular and cell biology, and neuroscience. Within the university are several research institutes with which the department has an extremely close association, including the McDonnell Center for Systems Neuroscience (website is under construction right now) and the Hope Center for Neurological Disorders. During the final year of pediatric neurology training, residents have up to nine months of elective time that they can dedicate to research if they so choose.


Resident Publication
Jacqueline Anderson Mills KI, Anderson J, Levy PT, et al. Duplication of 20p12.3 associated with familial Wolff-Parkinson-White syndrome. Am J Med Genet A. 2013;161A(1):137-144. [PMID: 23239491]
Jacqueline Anderson Anderson JL, Levy PT, Leonard KB, Smyser CD, Tychsen L, Cole FS. Congenital lymphocytic choriomeningitis virus: when to consider the diagnosis. J Child Neurol. 2014;29(6):837-842. [PMID: 23666045]
Nico Dosenbach Fair DA, Nigg JT, Iyer S, et al. Distinct neural signatures detected for ADHD subtypes after controlling for micro-movements in resting state functional connectivity MRI data. Front Syst Neurosci. 2013;6:80. Published 2013 Feb 4. [PMID: 23382713]
Alexander Fay Fay AJ, Mowry EM, Strober J, Waubant E. Relapse severity and recovery in early pediatric multiple sclerosis. Mult Scler. 2012;18(7):1008-1012. [PMID: 22183939]
Swati Karmarkar Saini A, Karmarkar SA, Rongkavilit C, et al. Index of suspicion. Pediatr Rev. 2013;34(1):41-46. [PMID: 23281361]
Katharine Meddles Hogeling M, Meddles K, Berk DR, et al. Extensive subcutaneous fat necrosis of the newborn associated with therapeutic hypothermia. Pediatr Dermatol. 2012;29(1):59-63. [PMID: 21906137]
Adam Ostendorf Myshrall TD, Moore SA, Ostendorf AP, et al. Dystroglycan on radial glia end feet is required for pial basement membrane integrity and columnar organization of the developing cerebral cortex. J Neuropathol Exp Neurol. 2012;71(12):1047-1063. [PMID: 23147502]
Adam Ostendorf Ostendorf AP, McKinstry RC, Shimony JS, Gutmann DH. Teaching NeuroImages: T2 hyperintensities in neurofibromatosis type 1. Neurology. 2013;80(20):e215-e216. [PMID: 23671349]


Resident Publication
Merveen Appu Appu M, Noetzel M. Clinically significant response to zolpidem in disorders of consciousness secondary to anti-N-methyl-D-aspartate receptor encephalitis in a teenager: a case report. Pediatr Neurol. 2014;50(3):262-264. [PMID: 24417935]
Shannon Liang Kitcharoensakkul M, Schulz CG, Kassel R, et al. Scurvy revealed by difficulty walking: three cases in young children. J Clin Rheumatol. 2014;20(4):224-228. [PMID: 24847751]
Sheel Pathak Prabhu AM, Pathak S, Khurana D, Legido A, Carvalho K, Valencia I. Nocturnal variant of benign myoclonic epilepsy of infancy: a case series. Epileptic Disord. 2014;16(1):45-49. [PMID: 24691296]
Sheel Pathak Al-Zubeidi D, Thangarajh M, Pathak S, et al. Fatal human herpesvirus 6-associated encephalitis in two boys with underlying POLG mitochondrial disorders. Pediatr Neurol. 2014;51(3):448-452. [PMID 25160553]


Resident Publication
Alexander Fay Fay AJ, Noetzel MJ, Mar SS. Pediatric Hemorrhagic Brainstem Encephalitis Associated With HHV-7 Infection. Pediatr Neurol. 2015;53(6):523-526. [PMID: 26255752]


Resident Publication
YoungMin Kim Ananth AL, Robichaux-Viehoever A, Kim YM, et al. Clinical Course of Six Children With GNAO1 Mutations Causing a Severe and Distinctive Movement Disorder. Pediatr Neurol. 2016;59:81-84. [PMID: 27068059]
Bittu Majmudar Koelman DL, Chahin S, Mar SS, et al. Acute disseminated encephalomyelitis in 228 patients: A retrospective, multicenter US study. Neurology. 2016;86(22):2085-2093. [PMID: 27164698]
Robert Rudock Loftspring MC, Landsness E, Wooliscroft L, Rudock R, Jo S, Patel KR. GABAB Encephalitis: A Fifty-Two-Year-Old Man with Seizures, Dysautonomia, and Acute Heart Failure. Case Rep Neurol Med. 2015;2015:812035. [PMID: 26609456]


Resident Publication
Bittu Majmudar Koelman DL, Benkeser DC, Xu Y, et al. Acute disseminated encephalomyelitis in China, Singapore and Japan: a comparison with the USA. Eur J Neurol. 2017;24(2):391-396. [PMID: 28009079]


Resident Publication
Shannon Agner Agner SC, Klein RS. Viruses have multiple paths to central nervous system pathology. Curr Opin Neurol. 2018;31(3):313-317. [PMID: 29561519]
Jasia Mahdi Mahdi J, Shah AC, Sato A, et al. A multi-institutional study of brainstem gliomas in children with neurofibromatosis type 1. Neurology. 2017;88(16):1584-1589. [PMID: 28330960]
Amanda Rogers Rogers A, Golumbek P, Cellini E, et al. De novo KCNA1 variants in the PVP motif cause infantile epileptic encephalopathy and cognitive impairment similar to recurrent KCNA2 variants. Am J Med Genet A. 2018;176(8):1748-1752. [PMID: 30055040]
Elizabeth Wright-Jin Avetisyan M, Rood JE, Huerta Lopez S, et al. Muscularis macrophage development in the absence of an enteric nervous system. Proc Natl Acad Sci U S A. 2018;115(18):4696-4701. [PMID: 29666241]


Resident Publication
Maria Galardi Galardi MM, Gaudioso C, Ahmadi S, Evans E, Gilbert L, Mar S. Differential Diagnosis of Pediatric Multiple Sclerosis. Children (Basel). 2019;6(6):75. Published 2019 Jun 3. [PMID: 31163654]
Cristina Gaudioso
Jasia Mahdi Griffith JL, Morris SM, Mahdi J, Goyal MS, Hershey T, Gutmann DH. Increased prevalence of brain tumors classified as T2 hyperintensities in neurofibromatosis 1. Neurol Clin Pract. 2018;8(4):283-291. [PMID: 30140579]
Regina Triplett Strahle JM, Triplett RL, Alexopoulos D, et al. Impaired hippocampal development and outcomes in very preterm infants with perinatal brain injury. Neuroimage Clin. 2019;22:101787. [PMID: 30991622]
Kimberly Wiltrout Wiltrout K, Ferrer A, van de Laar I, et al. Variants in DOCK3 cause developmental delay and hypotonia. Eur J Hum Genet. 2019;27(8):1225-1234. [PMID: 30976111]


Resident Publication
Jordan Cole Cole J, Evans E, Mwangi M, Mar S. Acute disseminated encephalomyelitis in children: an updated review based on current diagnostic criteria. Pediatr Neurol. 2019;100:26-34. [PMID: 31371120]
Cameron Crockett Crockett C, Joshi C, Rosenbaum M, Suneja M. Learning to drive: resident physicians' perceptions of how attending physicians promote and undermine autonomy. BMC Med Educ. 2019;19(1):293. [PMID: 31366383]
Maria Galardi Galardi MM, Strahle JM, Skidmore A, Kansagra AP, Guilliams KP. Cerebrovascular complications of pediatric blunt trauma. Pediatr Neurol. 2020;108:5-12. [PMID: 32111560]
Cristina Gaudioso Gaudioso C, Listernick R, Fisher MJ, et al. Neurofibromatosis 2 in children presenting during the first decade of life. Neurology. 2019;93(10):e964-e967. [PMID: 31363058]
Laura Gilbert Pearson TS, Gilbert L, Opladen T, et al. AADC deficiency from infancy to adulthood: symptoms and developmental outcome in an international cohort of 63 patients. J Inherit Metab Dis. 2020. Online ahead of print. [PMID: 32369189]
Jasia Mahdi Mahdi J, Goyal MS, Griffith J, Morris SM, Gutmann DH. Nonoptic pathway tumors in children with neurofibromatosis type 1. Neurology. 2020;95(8):e1052-e1059. [PMID: 32300062]
Elizabeth Wright-Jin Wright-Jin EC, Gutmann DH. Microglia as dynamic cellular mediators of brain function. Trends Mol Med. 2019;25(11):967-979. [PMID: 31597593]


Resident Publication
Saumel Ahmadi Leir SH, Yin S, Kerschner JL, Xia S, Ahmadi S, Bear C, Harris A. An organoid model to assay the role of CFTR in the human epididymis epithelium. Cell Tissue Res. 2020 Aug;381(2):327-336. Epub 2020 May 6. [PMID: 32377875]
Cameron Crockett Gedlinske AM, Stephan CM, Mockler SRH, Laubscher KM, Laubenthal KS, Crockett CD, Zimmerman MB, Mathews KD. Motor outcome measures in patients with FKRP mutations: A longitudinal follow-up. Neurology. 2020 Oct 13;95(15):e2131-e2139. Epub 2020 Aug 6. [PMID: 32764098]
Sarah Dixon Dixon SM, Binkley MM, Gospe SM Jr, Guerriero RM. Child Neurology Applicants Place Increasing Emphasis on Quality of Life Factors. Pediatr Neurol. 2021 Jan;114:42-46. Epub 2020 Sep 30. [PMID: 33212334]
Maria Galardi

Xu J, Galardi MM, Pok B, Patel KK, Zhao CW, Andrews JP, Singla S, McCafferty CP, Feng L, Musonza ET, Kundishora AJ, Gummadavelli A, Gerrard JL, Laubach M, Schiff ND, Blumenfeld H. Thalamic Stimulation Improves Postictal Cortical Arousal and Behavior. J Neurosci. 2020 Sep 16;40(38):7343-7354. Epub 2020 Aug 21. [PMID: 32826310]

Lauzier DC, Galardi MM, Guilliams KP, Goyal MS, Amlie-Lefond C, Hallam DK, Kansagra AP. Pediatric Thrombectomy: Design and Workflow Lessons From Two Experienced Centers. Stroke. 2021 Apr;52(4):1511-1519. Epub 2021 Mar 11. [PMID: 33691502]

Cristina Gaudioso

Gaudioso C, Oo S, Mar S, et al. PedsQL Multiple Sclerosis Module Domain and Item Development: Qualitative Methods. Journal of Child Neurology. 2021 May:8830738211015016. [PMID: 34048290]

Gaudioso C, Naismith RT. Optimizing treatment strategies in paediatric, adult and late-onset multiple sclerosis. Brain. 2020 Oct 1;143(10):2866-2868. [PMID: 33103733]

Wong GJ, Gaudioso CM, Castro E, Sharifai N, Dahiya S, Dehner LP, Griffith JL. Clinical Reasoning: A 7-year-Old Boy with Acute Onset Altered Mental Status. Neurology. 2021 Apr 13:10.1212/WNL.0000000000012034. Epub ahead of print. [PMID: 33849990]

Laura Gilbert

Aravamuthan BR, Ueda K, Miao H, Gilbert L, Smith SE, Pearson TS. Gait features of dystonia in cerebral palsy. Dev Med Child Neurol. 2021 Jun;63(6):748-754. Epub 2021 Jan 7. [PMID: 33411352]

Aravamuthan BR, Fehlings D, Shetty S, Fahey M, Gilbert L, Tilton A, Kruer MC. Variability in Cerebral Palsy Diagnosis. Pediatrics. 2021 Feb;147(2):e2020010066. Epub 2021 Jan 5. [PMID: 33402528]]