Thio Lab

The research interests of Liu-Lin Thio, MD, PhD, are cellular neurophysiology, inhibitory glycine receptors and ketogenic diet. He holds clinic weekly, is consultant pediatric epileptologist for the Pediatric Cerebral Palsy Center and serves on the Pharmaceutical, Diagnostics and Therapeutics Subcommittee at St. Louis Children’s Hospital.

Principal investigator

Kwee Liu Lin Thio, MD

Professor of Neurology
Chief, Pediatric Epilepsy
Director, Pediatric Epilepsy Center

• Phone: 314-454-6120

  Thio lab

 

Top areas of pediatric care: ketogenic diet, glucose transporter 1 deficiency syndrome, pyruvate dehydrogenase complex deficiency

Recent publications

• The role of copy number variants in the genetic architecture of common familial epilepsies
  March 1, 2024
  The role of copy number variants in the genetic architecture of common familial epilepsiesEpi4K Consortium, Mar 2024, In: Epilepsia. 65, 3, p. 792-804 13 p.Research output: Contribution to journal › Article › peer-review
• Subcutaneous deuterated substrate administration in mice: An alternative to tail vein infusion
  February 1, 2024
  Subcutaneous deuterated substrate administration in mice: An alternative to tail vein infusionSong, K. H., Ge, X., Engelbach, J. A., Thio, L. L., Neil, J. J., Ackerman, J. J. H. & Garbow, J. R., Feb 2024, In: Magnetic resonance in medicine. 91, 2, p. 681-686 6 p.Research output: Contribution to journal › Article › peer-review
• GWAS meta-analysis of over 29,000 people with epilepsy identifies 26 risk loci and subtype-specific genetic architecture
  September 1, 2023
  GWAS meta-analysis of over 29,000 people with epilepsy identifies 26 risk loci and subtype-specific genetic architectureInternational League Against Epilepsy Consortium on Complex Epilepsies, Sep 2023, In: Nature Genetics. 55, 9, p. 1471-1482 12 p.Research output: Contribution to journal › Article › peer-review
• Quantitative determination of SLC2A1 variant functional effects in GLUT1 deficiency syndrome
  May 1, 2023
  Quantitative determination of SLC2A1 variant functional effects in GLUT1 deficiency syndromeTayebi, N., Leon-Ricardo, B., McCall, K., Mehinovic, E., Engelstad, K., Huynh, V., Turner, T. N., Weisenberg, J., Thio, L. L., Hruz, P., Williams, R. S. B., De Vivo, D. C., Petit, V., Haller, G. & Gurnett, C. A., May 2023, In: Annals of Clinical and Translational Neurology. 10, 5, p. 787-801 15 p.Research output: Contribution to journal › Article › peer-review
• Epilepsy Milestones 2.0: An updated framework for assessing epilepsy fellowships and fellows
  August 1, 2022
  Epilepsy Milestones 2.0: An updated framework for assessing epilepsy fellowships and fellowsThio, L. L., Edgar, L., Ali, I., Farooque, P., Holland, K. D., Mizrahi, E. M., Shahid, A. M., Shin, H. W., Yoo, J. Y. & Carlson, C., Aug 2022, In: Epilepsia. 63, 8, p. 2155-2163 9 p.Research output: Contribution to journal › Article › peer-review