Diringer Lab
Michael N. Diringer, MD
All neonatal intensive care unit (NNICU) physicians have specialized research interests directed at improving the care we provide our patients. A unique aspect of this facility is that it is the only Neuro-ICU in the country with a positron emission tomography (PET) scanner located on site. The PET scanner is a tool that can measure brain blood flow and metabolism which are key factors in understanding the impact of our treatments. The PET room is equipped as any other ICU room and contains all the necessary equipment needed to care for a critically ill patient. The facility is funded by grants from the National Institutes of Health.
The NNICU also supports a wide range of other clinical investigations which complement our PET studies.
Current areas of active research include
- Time course of cerebral edema formation around intracerebral hemorrhage
- Glucose metabolism following intracerebral hemorrhage
- Effect of mannitol on sodium homeostasis and osmolality
- Impact of mannitol and hypertonic saline on CBF and brain volume
- Systemic inflammatory response in subarachnoid hemorrhage
- APO-e in subarachnoid hemorrhage
- Hemodynamic augmentation in subarachnoid hemorrhage
- Impact of stains on autoregulation in acute SAH
- Use of prothrombin complex in the reversal of coumadin induced coagulopathy
Principal investigator
Michael Diringer, MD
Professor, Neurology
Professor, Neurosurgery
Associate Professor, Anesthesiology
Associate Professor, Occupational Therapy
- Phone: 314-362-2999
Recent publications
- Optimal Design of Clinical Trials Involving Persons with Disorders of ConsciousnessCho, S. M., Robba, C., Diringer, M. N., Hanley, D. F., Hemphill, J. C., Horn, J., Lewis, A., Livesay, S. L., Menon, D., Sharshar, T., Stevens, R. D., Torner, J., Vespa, P. M., Ziai, W. C., Spann, M., Helbok, R. & Suarez, J. I., Feb 2024, In: Neurocritical Care. 40, 1, p. 74-80 7 p.Research output: Contribution to journal › Review article › peer-review
- Brain–Computer Interfaces for Communication in Patients with Disorders of Consciousness: A Gap Analysis and Scientific RoadmapSchiff, N. D., Diringer, M., Diserens, K., Edlow, B. L., Gosseries, O., Hill, N. J., Hochberg, L. R., Ismail, F. Y., Meyer, I. A., Mikell, C. B., Mofakham, S., Molteni, E., Polizzotto, L., Shah, S. A., Stevens, R. D. & Thengone, D., 2024, (Accepted/In press) In: Neurocritical Care.Research output: Contribution to journal › Article › peer-review
- Common Data Elements for Disorders of Consciousness: Recommendations from the Working Group on Neuroimagingand the Curing Coma Campaign and its Contributing Members, Dec 2023, In: Neurocritical Care. 39, 3, p. 611-617 7 p.Research output: Contribution to journal › Article › peer-review
- Common Data Elements for Disorders of Consciousness: Recommendations from the Working Group on Hospital Course, Confounders, and MedicationsCuring Coma Campaign, its contributing members, Dec 2023, In: Neurocritical Care. 39, 3, p. 586-592 7 p.Research output: Contribution to journal › Article › peer-review
- Hemodynamic Management in the Prevention and Treatment of Delayed Cerebral Ischemia After Aneurysmal Subarachnoid HemorrhageDeem, S., Diringer, M., Livesay, S. & Treggiari, M. M., Aug 2023, In: Neurocritical Care. 39, 1, p. 81-90 10 p.Research output: Contribution to journal › Article › peer-review