Parkinson Disease without Dementia
WHAT IS THE TITLE OF THE STUDY?
Understanding everyday cognitive functioning in Parkinson disease without dementia.
WHAT IS THE PURPOSE OF THE STUDY?
The overall purpose of this research is to learn how Parkinson disease affects thinking and memory in everyday life.
WHO IS NEEDED?
1) Volunteers must either be diagnosed with PD OR be healthy with no PD and with no first degree family member who has PD.
2) Volunteers can be males or females between 50 and 70 years of age.
3) Volunteers must not be experiencing any problems with thinking and memory that interfere with their daily activities.
4) PD volunteers must not have a history of other neurological problems besides PD. Healthy volunteers must not have any neurological problems such as a history of brain injury or tumor, stroke, seizures or movement disorders like tremors or tics.
5) Healthy volunteers cannot be the primary caregiver or spouse of someone with PD; healthy volunteers also cannot have a spouse who has participated in this study.
6) People taking certain medications or with other serious systemic health problems (e.g., heart failure) will be excluded.
WHAT IS INVOLVED IF I PARTICIPATE?
Duration: This study involves filling out questionnaires about your thinking and memory, mood, and daily activities; taking thinking and memory tests; performing certain simulated daily activities (e.g., meal preparation, paying bills); and having someone who knows you well fill out questionnaires about your thinking, memory and daily activities. The in-clinic testing session will take about 3 hours. The questionnaires you fill out will take under 30 minutes, and the questionnaires someone fills out about you will take under 10 minutes.
Tests/Procedures: Questionnaires, memory and thinking tests (interview and computer), simulated daily activity tests.
Risks: Risks will be discussed with volunteers as part of the informed consent process and involve mild discomforts like boredom, fatigue or frustration with some of the tests.
Benefits: There are no known direct benefits for participating in this study. Participation might help future patients with PD by leading to treatments that improve people's performance in daily activities that require thinking.
Compensation: Participants are compensated $40 for time and inconvenience. We will also cover your parking costs.
WHO IS THE PRINCIPAL INVESTIGATOR (DOCTOR)?
Erin R. Foster, OTD
WHERE WILL THE STUDY TAKE PLACE?
Washington University School of Medicine
Contact Information:
Coordinator Name: Deboragh Moore
Tel: (314) 362-5041 Email: moored@npg.wustl.edu
