Ms. Johanna Hartlein's research interest is movement disorders, primarily Parkinson Disease and Tourette Syndrome. The focus of her studies has been using brain imaging approaches, such as MRI and PET scan in combination with cognitive and memory testing to investigate brain function and activities in Parkinson Disease.
Ms. Johanna Hartlein got her Master of Science in Nursing from St. Louis University. Before she joined Movement Disorders Clinic, she served as a Staff Nurse in St.Louis Children's hospital. She is licensed family nurse practitioner in Missouri since 2006, and registered nurse since 1999. She is a member of several professional societies, including Parkinson Disease Association, Tourette Syndrome Association. Ms. Hartlein has many years of experience treating patients with Parkinson Disease and has been involved in many clinical studies in PD as well as other types of movement disorders.
Racette BA, Hartlein JM, Hershey T, Mink JW, Perlmutter JS, Black KJ: Clinical features and comorbidity of mood fluctuations in Parkinson's disease. J Neuropsychiatry Clin Neurosci 2002; 14(4):438-442.
Black KJ, Carl JL, Hartlein JM, Warren SL, Hershey T, Perlmutter JS: Rapid intravenous loading of levodopa for human research: Clinical results. J Neurosci Methods 2003; 127(1):19-29.
Hershey T, Black KJ, Hartlein JM, Barch DM, Braver TS, Carl JL, Perlmutter JS: Cognitive-pharmacologic fMRI in Tourette syndrome: A pilot study. Biol Psychiatry 2004; 55(9):916-925.
Hershey T, Black KJ, Hartlein JM, Braver TS, Barch DM, Carl JL, Perlmutter JS: Dopaminergic modulation of response inhibition: An fMRI study. Brain Res Cogn Brain Res 2004; 20(3):438-448.
Black KJ, Hershey T, Hartlein JM, Carl JL, Perlmutter JS: Levodopa challenge neuroimaging of levodopa-related mood fluctuations in Parkinson disease. Neuropsychopharmacology 2005; 30(3):590-601.
Wang L, Lee DY, Bailey E, Hartlein JM, Gado M, Miller MI, Black KJ: Validity of large-deformation high dimensional brain mapping of the thalamus and basal ganglia in adults with Tourette syndrome. Psychiatry Res. 2007 Feb 28;154(2):181-90. Epub 2007 Feb 7.
Gordon MR, Markham J, Hartlein JM, Koller JM, Loftin S, Black KJ: Intravenous levodopa administration in humans based on a tracer kinetic model. J Neurosci Methods. 2007 Jan 30;159(2):300-7. Epub 2006 Aug 24.
Karimi M, Golchin N, Tabbal SD, Hershey T, Videen TO, Wu J, Usche JW, Revilla FJ, Hartlein JM, Wernle AR, Mink JW, Perlmutter JS. Subthalamic nucleus stimulation-induced regional blood flow responses correlate with improvement of motor signs in Parkinson disease. Brain. 2008 Oct;131(Pt 10):2710-9. Epub 2008 Aug 12.
Burack, MA, Hartlein, JM, Flores, HP, Taylor-Reinwald, L, Perlmutter, JS, Cairns, NJ: In vivo amyloid imaging in autopsy-confirmed Parkinson disease dementia. Neurology 2010 Jan 5: 74(1):77-84. Epub 2010 Feb 1.
Washington University School of Medicine
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