Areas of Clinical Interest
Stroke, cerebrovascular disease, headache, migraine, general adult neurology

Areas of Research Interest
Clinical research in cerebrovascular disease.

Medical Training

Dr. Carpenter is the Medical Director of Clinical Stroke Services at Washington University, and is a co-director of the Washington University Moyamoya Center. He received his M.D. degree from Washington University School of Medicine in 1983, and trained in neurology at Washington University and Barnes-Jewish Hospital, completing his residency in 1988. After completing a research fellowship in stroke and cerebrovascular disease at Washington University, he remained on the faculty of the Department of Neurology at Washington University until 1993, when he went into private practice, maintaining an emphasis in stroke and cerebrovascular disease. He returned to the faculty in 2005, as a full-time clinical faculty member, and is active in the care of patients with stroke in the hospital, and of patients with both stroke and general neurological problems in the outpatient clinic, as well as supporting clinical research and cerebrovascular disease.

Selected Publications

Derdeyn CP, Carpenter DA, Videen TO, Grubb RL, Powers WJ. Patterns of infarction in hemodynamic failure. Cerebrovascular Diseases 2007;24:11-19.

Derdeyn CP. Videen TO. Yundt KD. Fritsch SM. Carpenter DA. Grubb RL. Powers WJ. Variability of cerebral blood volume and oxygen extraction: stages of cerebral haemodynamic impairment revisited. Brain 2002; 125(Pt 3):595-607

Derdeyn CP, Khosla A, Videen TO, Fritsch SM, Carpenter DL, Grubb RL Jr, Powers WJ. Severe hemodynamic impairment and border zone-region infarction. Radiology 2001;220(1):195-201

Derdeyn CP, Simmons NR, Videen TO, Yundt KD, Fritsch SM, Carpenter DL, Grubb RL, Powers WJ. Absence of selective deep white matter ischemia in chronic carotid disease: emission tomographic study of regional oxygen extraction. American Journal of Radiology 2000;21(4):631-8

Powers WJ, Derdeyn CP; Fritsch SM, Carpenter DA, Yundt KD, Videen TO, Grubb RL Jr. Benign prognosis of never-symptomatic carotid occlusion. Neurology 2000;54(4):878-82

Derdeyn CP, Videen TO, Fritsch SM, Carpenter DA, Grubb RL Jr, Powers WJ. Compensatory mechanisms for chronic cerebral hypoperfusion in patients with carotid occlusion. Stroke 1999;30(5):1019-24

Grubb RL Jr, Derdeyn CP, Fritsch SM, Carpenter DA, Yundt KD, Videen TO, Spitznagel EL, Powers WJ. Importance of hemodynamic factors in the prognosis of symptomatic carotid occlusion. JAMA 1998;280(12):1055-60

Derdeyn CP, Yundt KD, Videen TO, Carpenter DA, Grubb RL Jr., Powers WJ. Increased oxygen extraction fraction is associated with prior ischemic events in patients with carotid occlusion. Stroke 1998;29:754-758

Carpenter DA, Grubb RL Jr., Tempel WT, Powers WJ. Cerebral oxygen metabolism after aneurysmal subarachnoid hemorrhage. J Cereb Blood Flow Metab 1991;11:837-844

Carpenter DA, Grubb RL Jr., Powers WJ. Borderzone hemodynamics in cerebrovascular disease. Neurology 1990;40:1587-1592